默克索引 (1889)

《默克索引》（英语：Merck Index）是由美国默克公司出版的记录化学品、药物和生理性物质的综合性百科全书，收录超过一万多条有关个别的物质和其相关化合物的专题文章。本书亦于附录中收录有关有机化学的人名反应。默克索引亦设有订阅的电子检索形式，普遍被参考图书馆所采纳，以及在网上查阅的形式。有中译本。

默克索引于1889年首次出版，2013年起改由英国皇家化学学会（Royal Society of Chemistry）发行第15版，但仍维持原书名。

默克索引的专题文章函盖范围包括：

CAS号

物质的别名，例如俗名或IUPAC命名法

化学式

分子量

成分分析

结构式

对物质的外貌描述

熔点和沸点

在实验室常用溶剂之溶解性

根据物质的化学合成引述相关的文献和资料

在合适的情况下加入相关的医学用途

版本

第一版（1889年）

第二版（1896年）

第三版（1907年）

第四版（1930年）

第五版（1940年）

第六版（1952年）

第七版（1960年）

第八版（1968年）

第九版（1976年）

第十版（1983年）ISBN 0-911910-27-1

第十一版（1989年）ISBN 0-911910-28-X

第十二版（1996年）ISBN 0-911910-12-3

第十三版（2001年）ISBN 0-911910-13-1

第十四版（2006年）ISBN 978-0-911910-00-1

第十五版（2013年）ISBN 978-1-84973670-1

The Merck Index is an encyclopedia of chemicals, drugs and biologicals with over 10,000 monographs on single substances or groups of related compounds published online by the Royal Society of Chemistry.

History

The NFL edition of the Merck's Index was published in 1889 by the German chemical company Emanuel Merck and was primarily used as a sales catalog for Merck's growing list of chemicals it sold. The American subsidiary was established two years later and continued to publish it. During World War I the US government seized Merck's US operations Merck & Co., forming a separate American company that continued to publish the Merck Index.

In 2012 the Merck Index was licensed to the Royal Society of Chemistry. An online version of The Merck Index, including historic records and new updates not in the print edition, is commonly available through research libraries. It also includes an appendix with monographs on organic named reactions.

The 15th edition was published in April 2013.

Monographs in The Merck Index typically contain:

a CAS registry number synonyms of the substance, such as trivial names and International Union of Pure and Applied Chemistry nomenclature a chemical formula molecular weight percent composition a structural formula a description of the substance's appearance melting point and boiling point solubility in solvents commonly used in the laboratory citations to other literature regarding the compound's chemical synthesis a therapeutic category, if applicable caution and hazard information

Editions

1st (1889) – first edition released by E. Merck (Germany)

2nd (1896) – second edition released by Merck's American subsidiary and added medicines from the United States Pharmacopeia and National Formulary

3rd (1907)

4th (1930)

5th (1940)

6th (1952)

7th (1960) – first named editor is Merck chemist Paul G. Stecher

8th (1968) – editor Paul G. Stecher

9th (1976) – editor Martha Windholz, a Merck chemist

10th (1983), ISBN 0-911910-27-1 – editor Martha Windholz. In 1984 the Index became available online as well as printed.

11th (1989), ISBN 0-911910-28-X

12th (1996), ISBN 0-911910-12-3 – editor Susan Budavari, a Merck chemist

13th (2001), ISBN 0-911910-13-1 – editor Maryadele O'Neil, senior editor at Merck

14th (2006), ISBN 978-0-911910-00-1 – editor Maryadele O'Neil

15th (2013), ISBN 978-1-84973670-1 – editor Maryadele O'Neil; first edition under the Royal Society of Chemistry